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Proteomics Services for Cancer Research
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Proteomics Services for Cancer Research

Proteins are the functional molecules that drive cellular processes and are directly involved in disease pathways. At Alfa Cytology, we provide cutting-edge proteomics services to accelerate discoveries and advancements in the fight against cancer.

Overview of Cancer Proteomics

Cancer proteomics involves the comprehensive analysis of proteins in cancer cells, tissues, and biological fluids. It encompasses the identification, quantification, and characterization of proteins, as well as the exploration of their functional interactions. Through advanced mass spectrometry techniques, proteomics enables the profiling of protein expression patterns, post-translational modifications, and protein-protein interactions. The integration of proteomics data with genomics and transcriptomics provides a comprehensive view of the molecular alterations driving cancer progression and facilitates the development of personalized therapeutic strategies.

Fig 1. Workflow.Fig.1 Bottom-up proteomics workflow. (Urbiola-Salvador V, et al., 2022)

Our Services

At Alfa Cytology, we offer a comprehensive range of proteomics services tailored specifically for cancer research. Leveraging state-of-the-art technologies and a team of highly skilled scientists, we provide accurate and reliable data to support your research objectives. Our services include, but are not limited to:

Proteome Profiling

Using mass spectrometry techniques, we can identify and quantify thousands of proteins, providing a detailed snapshot of the proteomic landscape. By comparing protein expression profiles between cancer and normal samples, we can identify differentially expressed proteins that may serve as potential biomarkers or therapeutic targets.

Post-Translational Modification Analysis

Our comprehensive services enable the systematic characterization and quantification of post-translational modifications (PTMs), such as phosphorylation, acetylation, glycosylation, and ubiquitination. By elucidating the PTM patterns in cancer cells, we can uncover important regulatory mechanisms and identify novel targets for intervention.

Protein-Protein Interaction Network Analysis

Through our protein-protein interaction network analysis, we can identify and map the intricate web of protein interactions in cancer cells. This information can reveal key signaling pathways, protein complexes, and potential targets for therapeutic intervention.

Functional Pathway Analysis

Our functional pathway analysis service integrates proteomics data with existing knowledge databases to identify enriched pathways, biological functions, and molecular processes associated with the observed protein expression patterns.

Our Advantages

Comprehensive Proteomic Analysis

Our services offer a holistic and in-depth analysis of the cancer proteome, providing a comprehensive understanding of the molecular mechanisms underlying cancer development and progression.

Cutting-Edge Technology

We utilize advanced mass spectrometry platforms and bioinformatics tools to generate high-quality data. We enable sensitive and accurate protein identification and quantification.

Customized Solutions

We recognize the unique nature of each research project. Our team works closely with you to design tailored proteomics workflows that address your specific research questions and objectives.

Expertise and Experience

Our proteomics experts possess extensive knowledge and experience in cancer research. We are committed to delivering reliable results and advancing your research endeavors.

By utilizing cutting-edge techniques and a multidisciplinary approach, Alfa Cytology enables researchers to unlock the full potential of proteomics data, ultimately contributing to the development of personalized cancer therapies. If you are interested in our service, please contact us for more details.

Reference

  1. Urbiola-Salvador, V., et al.; (2022). Proteomics approaches to characterize the immune responses in cancer. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1869(8), 119266.

For research use only.