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Lung Cancer

Lung cancer is a type of cancer that originates from lung cells. It is one of the most common cancers in the world and a major cause of cancer-related deaths. Alfa Cytology is a world leader in the research of cancer. With our extensive experience and advanced platform, we can provide the best solutions for lung cancer.

Introduction to Lung Cancer

Lung cancer is mainly divided into two types, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Smoking is the cause of most lung cancer, but non-smokers may also develop lung cancer. Prevention and early detection are crucial for combating lung cancer. The estimated number of new lung cancer cases and deaths in the United States in 2024 is 234, 580 and 125, 070, respectively.

Therapy Development for Lung Cancer

The therapies for lung cancer include surgery, radiotherapy, chemotherapy, targeted therapy, immunotherapy, and a combination of these methods. The choice of method mainly depends on the stage or severity of the cancer, but other factors are also important, such as the overall health status and lung function of the body, as well as certain characteristics of the cancer itself.

The therapies for lung cancer include surgery, chemotherapy, radiation therapy, immunotherapy, and targeted therapy. Fig.1 The therapies for lung cancer. (Ashrafi, A., et al., 2022)

With the long-term research of disease targets and immune systems, targeted therapy and immunotherapy have become a new type of cancer therapy after surgery, chemotherapy, and radiotherapy because of their advantages of precision and small side effects. Here are a few examples of pharmaceutical companies and their drug development related to lung cancer.

Targets Therapeutics Company Molecule Type Phase
PD-1 MK-3475 Merck Monoclonal antibody
B7-H3 IgG1 Ifinatamab deruxtecan (MK-2400) Merck Antibody-drug conjugate
SEZ6 ABBV-706 Abbvie Antibody-drug conjugate
TIGIT Tiragolumab Genentech Monoclonal antibody

Our Services

Due to the complexity of lung cancer, developing effective lung cancer treatment methods faces certain challenges, such as high heterogeneity, genetic complexity, and acquired drug resistance. Therefore, Alfa Cytology is working on providing comprehensive solutions for lung cancer.

Types of Lung Cancer

Non-Small Cell Lung Cancer (NSCLC)

NSCLC is the most common type of lung cancer. The growth and diffusion rate of NSCLC is usually slower than that of SCLC.

  • Surgery
  • Targeted therapy
  • Immunotherapy

Small Cell Lung Cancer (SCLC)

Small cell lung cancer is not very common but extremely malignant and invasive, accounting for about 15-20% of lung cancer.

  • Radiation therapy
  • Chemotherapy

Therapy Development for Lung Cancer

Alfa Cytology is an experienced comprehensive contract research organization (CRO). We are proud to provide a range of therapy development services for lung cancer, including but not limited to the following.

Alfa Cytology is committed to the research and study of cancer and provides one-stop services. Our cancer experts have many years of experience in the development of the latest therapies for lung cancer. If you are interested in our service, please contact us for more information.

Reference

  1. Ashrafi, A., et al.; (2022). Current landscape of therapeutic resistance in lung cancer and promising strategies to overcome resistance. Cancers, 14(19), 4562.

For research use only.