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How to Select in Vivo Model for Cancer Immunotherapy Efficacy Assessment?

Selecting an in vivo model for cancer-immunotherapy efficacy hinges on aligning immune competence, tumor antigen presentation, and tumor-microenvironment fidelity with the therapeutic mechanism under study. Alfa Cytology provides syngeneic, humanized, cell-line–derived xenograft, and orthotopic mouse models that support rigorous preclinical evaluation across diverse tumor types.

Diverse of Preclinical Oncology Models

Capturing the complexity of tumor biology demands a spectrum of preclinical oncology models that reflect diverse immune contexts, genetic drivers, and microenvironmental cues. Alfa Cytology equips researchers with diverse in-vivo platforms—spanning syngeneic, humanized, genetically engineered, orthotopic, and cell-line–derived xenograft mouse models—to support rigorous evaluations of therapeutic efficacy and underlying mechanisms.

Patient-Derived Xenograft (PDX) Model

Cell Line-Derived Xenograft (CDX) Model

Genetically Engineered Model (GEM)

Syngeneic Mouse Tumor Model

Humanized Mouse Model

Tumor Metastatic Model

Our Focus Area

Alfa Cytology’s research portfolio covers a broad spectrum of malignancies, from breast and lung to gastric, bladder, and select hematologic cancers. This multi-cancer focus enables cross-disciplinary insight and tailored experimental models for diverse drug-discovery programs.

Prostate Cancer

Ovarian Cancer

Bladder Cancer

Brain Cancer

Liver Cancer

Renal Cell Carcinoma

Hematologic Cancer

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One-Stop Oncology Efficacy Service Platform

Tumor Model Library

  • Human/Mouse-Derived Tumor Cell Lines
  • Drug Resistant Cell Lines
  • Gene Editing Cell Lines
  • Human/Mouse CDX Models
  • Gene Engineered Models
  • Human/Mouse PDX
  • Humanized Mouse Models

In Situ Imaging Platform

  • Near-Infrared (NIR) Imaging
  • Positron Emission Tomography (PET)
  • Magnetic Resonance Imaging (MRI)
  • Ultrasound Imaging

In Vitro Analysis Platform

  • Flow Cytometry
  • Gene Expression Analysis
  • Western Blotting
  • Pathological Analysis
  • Blood Biochemistry Analysis

Armed with deep immuno-oncology expertise and validated preclinical platforms, Alfa Cytology stands ready to drive your efficacy studies with confidence and precision. Connect with us at any time to explore bespoke in-vivo strategies and obtain detailed support for your program.