| Size | 5 mg/25 mg |
| Purity | ≥98% |
| Formula | C29H23N5O3S |
| Molecule Mass | 521.59 |
| Chemical Name | 2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione |
| SMILES | O=C(C5=C4C(C6=O)=CC=CC4=CC=C5)N6CCCSC1=NN=C(C3=CC=NC=C3)N1C2=CC=C(OC)C=C2 |
| Target | Tankyrase |
| Biological Activity | WIKI4 is an inhibitor of Wnt/β-catenin signaling, with an EC50 of approximately 75 nM. It acts by inhibiting the auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ≈ 15 nM), which prevents the ubiquitination and subsequent degradation of axin. |
| Appearance | Solid |
| Color | Off-white to light yellow |
| Solubilization | The compound is soluble to 10 mM in DMSO |
| Storage | Store at -20°C |
| Shipping Information | Room temperature |
For preclinical research and development use only; not intended for therapeutic or other applications.
Alfa Cytology is a preclinical research service provider specializing in tumor organoid development. We provide one-stop services that include tailored 3D cancer models, organoid-based research services, and related products to accelerate the discovery and development of cancer therapeutics.
Copyright © 2026 Alfa Cytology. All rights reserved.