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Thiazovivin

Name: Thiazovivin
Brand: Alfa Cytology
SKU: SMOC-2603-CXX-042

Cat. No.: SMOC-2603-CXX-042

Description: A ROCK inhibitor that enhances the chemical reprogramming of fibroblasts into iPSCs.

Price: Inquiry

Datasheet: Datasheet

Product Details

Size	10 mg
Purity	≥98%
Formula	C15H13N5OS
Molecule Mass	311.36
Chemical Name	N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide
SMILES	O=C(NCC3=CC=CC=C3)C1=CSC(NC2=CC=NC=N2)=N1
Target	ROCK
Biological Activity	Thiazovivin is a selective, cell-permeable inhibitor of Rho-associated coiled-coil kinase (ROCK), with an IC50 of 0.5 μM. In combination with SB 431542 and PD 0325901, it enhances the efficiency of fibroblast reprogramming into iPSCs.
Appearance	Solid
Color	Off-white to light yellow
Solubilization	The compound is soluble to 100 mM in DMSO

Storage & Handling

Storage	Store at -20°C
Shipping Information	Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.