| Size | 10 mg/50 mg |
| Purity | ≥99% |
| Formula | C20H14N3OF |
| Molecule Mass | 331.35 |
| Chemical Name | 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol |
| SMILES | OC1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=NC=C1)C1=CC=C(F)C=C1 |
| Target | p38 MAPK |
| Biological Activity | SB 202190 is a highly selective, potent, and cell-permeable inhibitor of p38 MAP kinase. It binds within the ATP pocket of the active kinase (Kd = 38 nM for recombinant human p38) and selectively inhibits the p38α and p38β isoforms (IC50 = 50 nM for SAPK2a/p38 and 100 nM for SAPK2b/p38β2). |
| Appearance | Solid |
| Color | Off-white to yellow |
| Solubilization | The compound is soluble to 100 mM in DMSO |
| Storage | Store at -20°C |
| Shipping Information | Room temperature |
For preclinical research and development use only; not intended for therapeutic or other applications.
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