banner
Online Inquiry

SANT-1

Cat. No.: SMOC-2603-CXX-036

Description: A Hedgehog pathway inhibitor that acts as a high-affinity Smoothened (Smo) antagonist.

Price: Inquiry

Datasheet: Datasheet

Product Details

Size 10 mg/50 mg
Purity ≥98%
Formula C23H27N5
Molecule Mass 373.5
Chemical Name N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
SMILES CC1=NN(C(C)=C1\C=N\N1CCN(CC2=CC=CC=C2)CC1)C1=CC=CC=C1
Target Hedgehog (Hh) signaling
Biological Activity SANT-1 is a potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling, acting as a high-affinity antagonist of the Smoothened receptor (Kd = 1.2 nM).
Appearance Solid
Color White to off-white
Solubilization The compound is soluble to 50 mM in DMSO

Storage & Handling

Storage Store at +4°C
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.