| Size | 10 mg/50 mg |
| Synonyms | E-616452, SJN 2511, ALK5 Inhibitor II |
| Purity | ≥99% |
| Formula | C17H13N5 |
| Molecule Mass | 287.32 |
| Chemical Name | 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine |
| SMILES | CC1=NC(C2=NNC=C2C4=NC3=CC=CN=C3C=C4)=CC=C1 |
| Target | TGF-βRI |
| Biological Activity | RepSox is a potent and selective inhibitor of the TGF-β type I receptor ALK5, with IC50 values of 4 nM for autophosphorylation and 23 nM for binding. |
| Appearance | Solid |
| Color | Light brown to yellow |
| Solubilization | The compound is soluble to 100 mM in DMSO and to 20 mM in ethanol |
| Storage | Store at +4°C |
| Shipping Information | Room temperature |
For preclinical research and development use only; not intended for therapeutic or other applications.
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