| Size | 10 mg/50 mg |
| Synonyms | Palbociclib |
| Purity | ≥98% |
| Formula | C24H29N7O2.C2H6O4S |
| Molecule Mass | 573.66 |
| Chemical Name | 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one isethionate salt |
| SMILES | O=C1C(C(C)=O)=C(C)C(C=NC(NC4=NC=C(N5CCNCC5)C=C4)=N3)=C3N1C2CCCC2.OCCS(=O)(O)=O |
| Target | Cdk4, Cdk6 |
| Biological Activity | PD 0332991 isethionate is a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and CDK6, with IC50 values of 11 nM and 15 nM, respectively. |
| Appearance | Solid |
| Color | Light yellow to yellow |
| Solubilization | The compound is soluble to 100 mM in water and to 10 mM in DMSO |
| Storage | Store at room temperature. |
| Shipping Information | Room temperature |
For preclinical research and development use only; not intended for therapeutic or other applications.
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