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PD 0325901

Cat. No.: SMOC-2603-CXX-029

Description: A highly effective antagonist of the MAP kinase kinases MEK1 and MEK2.

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Datasheet: Datasheet

Product Details

Size 10 mg/50 mg
Synonyms PD325901
Purity ≥99%
Formula C16H14F3IN2O4
Molecule Mass 482.19
Chemical Name N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide
SMILES FC1=CC(I)=CC=C1NC2=C(C(NOC[C@H](O)CO)=O)C=CC(F)=C2F
Target MEK1/2
Biological Activity PD 0325901 is a potent inhibitor of MEK1 and MEK2, suppressing MEK activity in mouse colon 26 cells with an IC50 of 0.33 nM.
Appearance Solid
Color White to off-white
Solubilization The compound is soluble to 25 mM in DMSO

Storage & Handling

Storage Store at -20°C
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.