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NIBR LTSi

Cat. No.: SMOC-2603-CXX-027

Description: A potent LATS inhibitor that promotes YAP nuclear translocation and signaling.

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Datasheet: Datasheet

Product Details

Size 10 mg/50 mg
Purity ≥98%
Formula C18H20N4O
Molecule Mass 308.39
Chemical Name N-[4-[(3R)-Piperidin-3-yl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridin-4-amine
SMILES C1(NC2=CC=C(O[C@H]3CNCCC3)C=C2)=CC=NC4=C1C=CN4
Target LATS
Biological Activity NIBR-LTSi is a potent and selective inhibitor of large tumor suppressor kinase (LATS), with an IC50 of 1.4 nM.
Appearance Solid
Color White to off-white
Solubilization The compound is soluble to 100 mM in DMSO

Storage & Handling

Storage Store at -20°C
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.