Cat. No.: RONO-2603-CXX-015
Description: Mouse liver organoids are derived from embryonic or neonatal mouse liver tissue, enabling parallel isolation of hepatic progenitor cells (HPCs), liver mesenchymal cells (LMCs), and liver sinusoidal endothelial cells (LSECs) to minimize donor variability while preserving stemness and physiological relevance.
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| Advantages | These organoids typically form cystic or solid spheroids and branching cholangiocyte-like structures with bile canaliculi-like networks; Kupffer cells and hepatic stellate cells can be incorporated to model immune and fibrotic responses. Leveraging the small size, short breeding cycles, and ease of husbandry of mice, these organoids are widely used for modeling liver diseases (metabolic, inflammatory, fibrotic), drug screening, DILI/toxicology studies, ADME/DMPK profiling, and investigating liver–immune crosstalk. |
| Species | Mouse |
| Product Type | Tissue-derived Organoid |
| Growth Properties | Embedded 3D Culture |
| Growth Conditions | Cultured at 37°C under 95% air and 5% CO2. |
| Quality Control | Negative for mycoplasma, bacteria, yeast, and fungi. |
| Tissue | Liver |
| Disease | Normal |
| Format | Frozen |
| Organoid Characterization | All batches are screened for mycoplasma, bacteria, and fungi/yeast, and verified for identity, genetic stability, and functional performance including albumin secretion, urea production, and CYP450 induction. |
| Applications | Tissue-derived organoids are widely applied in drug screening, disease modeling, mechanistic studies, personalized medicine, and regenerative medicine. Through accurate modeling of disease states, they provide an ideal platform for evaluating patient-specific responses to novel therapeutics and informing personalized treatment strategies. Additionally, these organoids drive the development of novel therapeutic modalities, particularly in oncology and tissue regeneration, offering sophisticated experimental tools that accelerate progress in precision medicine. |
| Storage | Liquid Nitrogen |
| Shipping Information | Dry Ice |
For preclinical research and development use only; not intended for therapeutic or other applications.
Alfa Cytology is a preclinical research service provider specializing in tumor organoid development. We provide one-stop services that include tailored 3D cancer models, organoid-based research services, and related products to accelerate the discovery and development of cancer therapeutics.
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