| Size | 10 mg/50 mg |
| Purity | ≥98% |
| Formula | C22H18N4O2S3 |
| Molecule Mass | 466.6 |
| Chemical Name | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| SMILES | O=C1C3=C(CCS3)N=C(SCC(NC4=NC(C=CC(C)=C5)=C5S4)=O)N1C2=CC=CC=C2 |
| Target | PORCN |
| Biological Activity | IWP 2 is a potent inhibitor of Wnt processing and secretion (IC50 = 27 nM). It achieves this by inactivating PORCN, a member of the membrane-bound O-acyltransferase (MBOAT) family, thereby selectively blocking Wnt palmitoylation. |
| Appearance | Solid |
| Color | White to off-white |
| Solubilization | The compound is soluble to 5 mM in DMSO with gentle warming |
| Storage | Store at +4°C |
| Shipping Information | Room temperature |
For preclinical research and development use only; not intended for therapeutic or other applications.
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