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Iressa

Cat. No.: SMOC-2603-CXX-019

Description: A selective, orally bioavailable inhibitor of EGFR tyrosine kinase.

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Datasheet: Datasheet

Product Details

Size 10 mg/50 mg
Synonyms Gefitinib, ZD 1839
Purity ≥98%
Formula C22H24ClFN4O3
Molecule Mass 446.9
Chemical Name N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine
SMILES FC(C=C3)=C(Cl)C=C3NC2=NC=NC1=CC(OC)=C(OCCCN4CCOCC4)C=C12
Target EGFR
Biological Activity Iressa is an orally active, selective EGFR tyrosine kinase inhibitor (IC50 = 23–79 nM) with minimal activity against ErbB2, KDR, c-Flt, PKC, MEK, and ERK-2.
Appearance Solid
Color White to off-white
Solubilization The compound is soluble to 100 mM in DMSO and to 10 mM in ethanol

Storage & Handling

Storage Store at room temperature.
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.