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Human Proximal Renal Tubular Model

Cat. No.: ROOC-2603-CXX-003

Description: A human primary proximal renal tubule model has been developed that preserves renal tubular epithelial cell differentiation and supports stem cell maintenance. This system provides an ideal in vitro platform for renal function research, drug absorption studies, and nephrotoxicity assessment.

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Product Details

Advantages When cultured under dynamic conditions in a microfluidic system, human primary renal proximal tubule epithelial cells proliferate more rapidly than in traditional Transwell formats. This dynamic model also develops tighter barrier integrity and exhibits enhanced transmembrane transporter activity.
Species Human
Product Type Organoid-on-a-Chip
Disease Normal

Application

Applications Supports nephrotoxicity screening, mechanistic investigation of renal injury, and disease modeling of kidney pathologies.

For preclinical research and development use only; not intended for therapeutic or other applications.