| Advantages | Lacrimal gland organoids exhibiting comparable histology, expression of key markers, and functional responses including pilocarpine-induced calcium signaling and β-hexosaminidase release. |
| Species | Human |
| Product Type | Adult Tissue-derived Organoid |
| Quality Control | Negative for mycoplasma, bacteria, yeast, and fungi. |
| Tissue | Lacrimal gland |
| Disease | Gland Disease Model |
| Organoid Characterization | Histological analysis of lacrimal gland organoids using H&E and Alcian blue staining reveals acinar cell structures and acidic mucin secretion. PAS staining demonstrates the presence of glycogen and glycoproteins, while Masson's Trichrome staining identifies keratin as a major extracellular matrix component. Expression patterns of VIM, AQP5, and LYZ within the organoids closely parallel those of native acinar cells. |
| Applications | This system enables more predictive drug screening, disease modeling, and regenerative research by authentically representing lacrimal gland biology. |
| Storage | Liquid Nitrogen |
| Shipping Information | Dry Ice |
For preclinical research and development use only; not intended for therapeutic or other applications.