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Human Lacrimal Gland Organoid

Cat. No.: RONO-2603-CXX-057

Description: Lacrimal gland organoids faithfully recapitulate native tear-gland tissue.

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Product Details

Advantages Lacrimal gland organoids exhibiting comparable histology, expression of key markers, and functional responses including pilocarpine-induced calcium signaling and β-hexosaminidase release.
Species Human
Product Type Adult Tissue-derived Organoid
Quality Control Negative for mycoplasma, bacteria, yeast, and fungi.
Tissue Lacrimal gland
Disease Gland Disease Model
Organoid Characterization Histological analysis of lacrimal gland organoids using H&E and Alcian blue staining reveals acinar cell structures and acidic mucin secretion. PAS staining demonstrates the presence of glycogen and glycoproteins, while Masson's Trichrome staining identifies keratin as a major extracellular matrix component. Expression patterns of VIM, AQP5, and LYZ within the organoids closely parallel those of native acinar cells.

Application

Applications This system enables more predictive drug screening, disease modeling, and regenerative research by authentically representing lacrimal gland biology.

Storage & Handling

Storage Liquid Nitrogen
Shipping Information Dry Ice

For preclinical research and development use only; not intended for therapeutic or other applications.