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Human iPSC-Derived Colon Organoid

Cat. No.: RONO-2603-CXX-045

Description: Human iPSC-derived colon organoids are advanced 3D cell models generated through directed differentiation of human induced pluripotent stem cells.

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Product Details

Advantages With thorough quality control processes, these organoids ensure high reproducibility, scalability, and genetic consistency, making them valuable for diverse biomedical research applications.
Species Human
Product Type iPSC-derived Organoid
Growth Properties Embedded 3D Culture
Growth Conditions Cultured at 37°C under 95% air and 5% CO2.
Quality Control Negative for mycoplasma, bacteria, yeast, and fungi.
Tissue Colon
Disease Normal
Format Frozen
Organoid Characterization They replicate the architecture and physiological functions of the human colon, displaying self-organizing properties and complex biological behaviors that resemble native tissue. These organoids recapitulate the structure and function of the human intestine and incorporate multiple cell types, including MUC2+ goblet cells, EPHB2+ transit amplifying (TA) cells, VILLIN+ epithelial cells, and Chromogranin A (CHGA+) endocrine cells, all integral to their complex architecture.

Application

Applications iPSC-derived organoids are used across diverse research fields, including disease modeling, drug discovery, gene therapy evaluation, and personalized medicine. They can replicate a wide range of disease states, providing reliable platforms for studying neurodegenerative disorders, cancer, cardiovascular conditions, and more. These organoids are also valuable for drug efficacy and safety testing, tissue regeneration studies, and investigating host-microbe interactions, driving innovation in biomedical research.

Storage & Handling

Storage Liquid Nitrogen
Shipping Information Dry Ice

For preclinical research and development use only; not intended for therapeutic or other applications.