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Erlotinib Hydrochloride

Cat. No.: SMOC-2603-CXX-014

Description: A potent and reversible inhibitor of EGFR-associated tyrosine kinase activity.

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Datasheet: Datasheet

Product Details

Size 50 mg
Purity ≥98%
Formula C22H23N3O4.HCl
Molecule Mass 429.9
Chemical Name N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
SMILES Cl.C#CC1=CC=CC(=C1)NC=2N=CN=C3C=C(OCCOC)C(OCCOC)=CC32
Target EGFR
Biological Activity Erlotinib hydrochloride is a potent and reversible EGFR tyrosine kinase inhibitor (IC50 = 2 nM), reducing EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM.
Appearance Solid
Color White to off-white
Solubilization The compound is soluble to 20 mM in DMSO

Storage & Handling

Storage Store at -20°C
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.