| Size | 10 mg/50 mg |
| Synonyms | GSI-IX |
| Purity | ≥99% |
| Formula | C23H26F2N2O4 |
| Molecule Mass | 432.46 |
| Chemical Name | (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester |
| SMILES | CC(C)(C)OC([C@H]([C@]2=CC=CC=C2)NC([C@H](C)NC(CC1=CC(F)=CC(F)=C1)=O)=O)=O |
| Target | γ-secretase |
| Biological Activity | DAPT is a γ-secretase inhibitor that reduces levels of Aβ40 and Aβ42, with IC50 values of 115 nM for total Aβ and 200 nM for Aβ42 in human primary neuronal cultures. |
| Appearance | Solid |
| Color | White to off-white |
| Solubilization | The compound is soluble to 100 mM in DMSO |
| Storage | Store at +4°C |
| Shipping Information | Room temperature |
For preclinical research and development use only; not intended for therapeutic or other applications.
Alfa Cytology is a preclinical research service provider specializing in tumor organoid development. We provide one-stop services that include tailored 3D cancer models, organoid-based research services, and related products to accelerate the discovery and development of cancer therapeutics.
Copyright © 2026 Alfa Cytology. All rights reserved.