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Chroman 1

Cat. No.: SMOC-2603-CXX-006

Description: A potent, selective ROCK2 inhibitor that enhances post-thaw cell viability following cryopreservation.

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Datasheet: Datasheet

Product Details

Size 10 mg/50 mg
Purity ≥98%
Formula C24H28N4O4.2HCl
Molecule Mass 509.43
Chemical Name (3S)-N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-3,4-dihydro-6-methoxy-2H-1-benzopyran-3-carboxamide dihydrochloride
SMILES COC1=CC=C2OC[C@@H](C(NC3=C(C=C(C4=CNN=C4)C=C3)OCCN(C)C)=O)CC2=C1.Cl.Cl
Target ROCK 2
Biological Activity Chroman 1 is a highly potent and selective ROCK2 inhibitor, with IC50 values of 1 pM for ROCK2 and 52 pM for ROCK1.
Appearance Solid
Color White to pink
Solubilization The compound is soluble to 100 mM in DMSO and to 5 mM in water

Storage & Handling

Storage Store at -20°C
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.