banner
Online Inquiry

Blood-brain Barrier Model

Cat. No.: ROOC-2603-CXX-004

Description: The blood-brain barrier (BBB), a component of the neurovascular unit, forms a selective interface between cerebral capillaries and neural tissue, tightly regulating molecular exchange between blood and brain. A microfluidic BBB model has been developed that exhibits robust barrier function and high physiological relevance, making it a valuable tool for studying human BBB integrity and evaluating brain penetration of drug candidates.

Price: Inquiry

Datasheet: Datasheet

Product Details

Advantages Relative to conventional Transwell systems, this microfluidic BBB model displays superior barrier properties, including elevated tight junction protein expression, increased transendothelial electrical resistance, and reduced apparent permeability.
Species Human
Product Type Organoid-on-a-Chip
Disease Normal

Application

Applications Enables evaluation of blood-brain barrier penetration, efficacy testing against primary and metastatic brain tumors, and toxicity assessment on cerebral microvascular cells.

For preclinical research and development use only; not intended for therapeutic or other applications.