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16,16-Dimethyl Prostaglandin E2

Cat. No.: SMOC-2603-CXX-001

Description: A synthetic PGE2 analog that modulates hematopoietic stem cell (HSC) development.

Price: Inquiry

Datasheet: Datasheet

Product Details

Size 1 mg
Purity ≥95%
Formula C22H36O5
Molecule Mass 380.52
Chemical Name (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid
SMILES O=C1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)C(C)(C)CCCC)[C@H](O)C1
Target EP2, EP4
Biological Activity 16,16-Dimethyl Prostaglandin E2, a synthetic analog of Prostaglandin E2, promotes hematopoietic colony formation from embryonic stem cells (ESCs) in mouse bone marrow. Furthermore, it expands the hematopoietic stem cell (HSC) pool and potentiates Wnt signaling within the HSC compartment in zebrafish embryos.
Appearance Liquid
Color Colorless to light yellow
Solubilization Dissolves in methyl acetate; supplied as a 10 mg/mL solution.

Storage & Handling

Storage Store at -80°C
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.