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Staurosporine

Cat. No.: SMOC-2603-CXX-040

Description: A broad-spectrum inhibitor of various protein kinases.

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Datasheet: Datasheet

Product Details

Size 100 ug
Synonyms AM-2282
Purity ≥98%
Formula C28H26N4O3
Molecule Mass 466.54
Chemical Name [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
SMILES O=C(NC6)C1=C6C4=C3C2=C1C8=C(C=CC=C8)N2[C@](C[C@@H](NC)[C@H]7OC)([H])O[C@]7(C)N3C5=CC=CC=C45
Biological Activity Staurosporine is a broad-spectrum protein kinase inhibitor, potently inhibiting PKC (IC50 = 3 nM), p60v-src (IC50 = 6 nM), PKA (IC50 = 7 nM), and CaM kinase II (IC50 = 20 nM). 
Appearance Solid
Color White to yellow
Solubilization The compound is soluble to 50 mM in DMSO

Storage & Handling

Storage Store at -20°C
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.