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SRT 1720

Cat. No.: SMOC-2603-CXX-039

Description: A selective SIRT1 activator that triggers autophagy and enhances mitochondrial biogenesis.

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Datasheet: Datasheet

Product Details

Size 10 mg/50 mg
Purity ≥98%
Formula C25H23N7OS
Molecule Mass 469.56
Chemical Name N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide
SMILES O=C(NC=1C=CC=CC1C=2N=C3SC=C(N3C2)CN4CCNCC4)C5=NC6=CC=CC=C6N=C5
Target SIRT1
Biological Activity SRT 1720 is a selective activator of SIRT1, with an EC50 of 0.16 μM. It inhibits the growth of bladder cancer organoids and xenografts (IC50 = 0.35 μM) and induces autophagy.
Appearance Solid
Color Light yellow to yellow
Solubilization The compound is soluble to 5 mM in DMSO

Storage & Handling

Storage Store at -20°C
Shipping Information Room temperature

For preclinical research and development use only; not intended for therapeutic or other applications.