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Human Retinal Organoid

Cat. No.: RONO-2603-CXX-054

Description: Retinal organoids provide a reliable system for investigating retinal development, disease pathology, and therapeutic candidates.

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Product Details

Species Human
Product Type iPSC-derived Organoid
Quality Control Negative for mycoplasma, bacteria, yeast, and fungi.
Tissue Retinal
Disease Normal
Generation Process Stable and reproducible retinal organoids derived from human pluripotent stem cells (hPSCs) are generated using advanced differentiation protocols. These models recapitulate the complex architecture of the retina, providing an ideal platform for translational research in vision science.
Organoid Characterization The human retina is broadly divided into the neural retina and the retinal pigmented epithelium. Retinal organoids express specific markers corresponding to each retinal layer. By approximately day 25 of culture, retinal ganglion cell and bipolar cell layers are observed, accompanied by expression of the marker Pax6. Analysis of cellular organization within the organoid, together with expression of the photosensitive cell marker Recoverin, confirms that these retinal organoids closely resemble native human retinal tissue.

Application

Applications These models support accurate drug screening for conditions including retinitis pigmentosa and age-related macular degeneration, accelerating advances in vision science and treatment innovation.

Storage & Handling

Storage Liquid Nitrogen
Shipping Information Dry Ice

For preclinical research and development use only; not intended for therapeutic or other applications.