| Species | Human |
| Product Type | iPS-derived Organoid |
| Quality Control | Negative for mycoplasma, bacteria, yeast, and fungi. |
| Tissue | Brain (Midbrain) |
| Disease | Parkinson’s Disease, Brain & CNS Disease Model |
| Generation Process | Human pluripotent stem cell (hPSC)-derived midbrain organoids, generated using optimized differentiation protocols, support long-term culture and mature into advanced models enriched with functional dopamine neurons. These organoids provide a reliable system for investigating neurodevelopment and neurodegenerative diseases such as Parkinson's disease. |
| Organoid Characterization | Midbrain organoids recapitulate key genetic and structural characteristics of the human midbrain. They contain abundant dopamine neurons alongside a variety of supporting cell types. With extended culture, these organoids develop melanin deposition in the substantia nigra, a distinctive hallmark unique to the human midbrain. |
| Applications | By recapitulating the key structures and cell types of the human midbrain, they enable more predictive assessment of drug efficacy and toxicity, reduce dependence on animal models, and generate insights that translate more directly to clinical outcomes. |
| Storage | Liquid Nitrogen |
| Shipping Information | Dry Ice |
For preclinical research and development use only; not intended for therapeutic or other applications.
Alfa Cytology is a preclinical research service provider specializing in tumor organoid development. We provide one-stop services that include tailored 3D cancer models, organoid-based research services, and related products to accelerate the discovery and development of cancer therapeutics.
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