| Advantages | This stage is ideal for studying dopamine neuron development and modeling neurodegenerative diseases, offering a more advanced platform for therapeutic research. |
| Species | Human |
| Product Type | iPSC-derived Organoid |
| Growth Properties | Embedded 3D Culture |
| Growth Conditions | Cultured at 37°C under 95% air and 5% CO2. |
| Quality Control | Negative for mycoplasma, bacteria, yeast, and fungi. |
| Tissue | Midbrain |
| Disease | Normal |
| Format | Frozen |
| Organoid Characterization | SEM imaging reveals spherical, healthy neuronal populations with maturation kinetics aligned to human cortical development. By 4 months, these organoids exhibit significant maturation, with dopaminergic neurons beginning to form functional networks. Each batch is rigorously screened for mycoplasma, bacteria, and fungi/yeast, and validated for identity, genetic stability, and functional performance. |
| Applications | Human iPSC-derived midbrain organoids are 3D models produced from human induced pluripotent stem cells through directed differentiation. They closely mimic native tissue architecture and function, demonstrating self-organizing properties and physiologically relevant behaviors. Rigorous quality control ensures high reproducibility, scalability, and genetic integrity, positioning them as ideal platforms for a wide range of biomedical research. These models recapitulate brain cellular composition and exhibit strong expression of TH (dopaminergic neuron marker) along with FOXA2 and OTX2 (dopaminergic progenitor markers). They also display functional features, including spontaneous neuronal activity. |
| Storage | Liquid Nitrogen |
| Shipping Information | Dry Ice |
For preclinical research and development use only; not intended for therapeutic or other applications.
Alfa Cytology is a preclinical research service provider specializing in tumor organoid development. We provide one-stop services that include tailored 3D cancer models, organoid-based research services, and related products to accelerate the discovery and development of cancer therapeutics.
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