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Human iPSC-Derived Forebrain Organoid (4 month)

Cat. No.: RONO-2603-CXX-005

Description: Human iPSC-derived forebrain organoids cultured for four months (120 days) display mature electrophysiological properties, including action potential firing and measurable sodium and potassium currents.

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Product Details

Advantages These organoids are well-suited for neurodevelopment studies, drug screening, and modeling forebrain diseases such as Alzheimer's disease.
Species Human
Product Type iPSC-derived Organoid
Growth Properties Embedded 3D Culture
Growth Conditions Cultured at 37°C under 95% air and 5% CO2.
Quality Control Negative for mycoplasma, bacteria, yeast, and fungi.
Tissue Forebrain
Disease Normal
Format Frozen
Organoid Characterization Patterned with key developmental factors, they differentiate into forebrain cortical cells according to the human forebrain developmental timeline and express dorsal forebrain markers FoxG1, Otx2, and Emx1.

Application

Applications Forebrain cortical organoids generated from human iPSC lines are sophisticated 3D models that replicate in vivo cortical cell-cell interactions. These models support research in human brain biology, disease pathogenesis, and drug candidate testing, including neurotoxicity screening, target engagement studies, and mechanism-of-action analyses.

Storage & Handling

Storage Liquid Nitrogen
Shipping Information Dry Ice

For preclinical research and development use only; not intended for therapeutic or other applications.