| Size | 10 mg/50 mg |
| Purity | ≥98% |
| Formula | C25H19N5S |
| Molecule Mass | 421.52 |
| Chemical Name | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
| SMILES | S=C(NC5=CC=CC=C5)N(N=C3C4=NC(C)=CC=C4)C=C3C2=CC=NC1=CC=CC=C12 |
| Target | TGF-βRI, ALK4 and ALK7 |
| Biological Activity | A 83-01 is a potent inhibitor of the TGF-β type I receptor ALK5, as well as the activin/nodal receptors ALK4 and ALK7, with IC50 values of 12, 45, and 7.5 nM, respectively. |
| Appearance | Solid |
| Color | Off-white to light yellow |
| Solubilization | The compound is soluble to 50 mM in DMSO |
| Storage | Store at -20°C |
| Shipping Information | Room temperature |
For preclinical research and development use only; not intended for therapeutic or other applications.
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